Research Areas

Bioinformatics concerns application of advanced modeling, optimization and information science techniques necessary to integrate data from research in genomics, molecular evolution and macromolecular structure/function relationships to provide understanding of biological systems at different levels of complexity. We develop novel optimization models and efficient solution algorithms for DNA sequencing, classification of protein structures, estimation of 3D protein structures, analysis of metabolic networks, and computer-aided drug design.
People: Ceyda Oğuz, Metin Türkay
Data Mining
Data mining, which is defined as searching for useful patterns in huge amounts of data, is a critical component of the Customer Relationship Management efforts. Our research in this area relates to customer segmentation and valuation, sales response analysis, risk classification. Our efforts in this area include modeling of challenging business problems as well as algorithm development.
People: Özden Gür Ali, Sibel Salman, Serpil Sayın
Financial Engineering
Optimization and stochastic analysis tools of operations research and management sciences are used quite effectively in order to evaluate financial markets, determine investment strategies, as well as design, engineer and market new financial products. The topic has become more appealing with the emergence of new securities and financial instruments, like options, swaps, interest rate derivatives, retirement plans, etc. Research on financial engineering focuses on a variety of topics including portfolio optimization, pricing of derivative securities and computational finance.
People: Süleyman Özekici
As defined by the Council of Logistics Management in the U.S.A.
"logistics is that part of the supply chain process that plans, implements, and controls the efficient, effective flow and storage of goods, services, and related information from the point-of-origin to the point-of-consumption in order to meet customers' requirements" (
Our research in logistics aims at complementing the research in supply chain management. Therefore, the topics we are interested in are primarily location of facilities, managing warehouses, transportation management, and fleet management. We develop optimization models for the planning, organizing, and controlling of logistics systems and provide exact or approximation solutions to the problems that may arise in logistics systems. We are particularly interested in vehicle routing problems, location problems, and the interaction of elements in the whole logistics network.
People: Deniz Aksen, Onur Kaya, Ceyda Oğuz, Sibel Salman, Metin Türkay
Optimization Theory and Algorithms
Research in this area are focuses mainly on the design and analysis of efficient solution methods to a range of optimization problems including those with combinatorial multicriteria and uncertainty aspects. Ongoing work spans understanding the nature of the complexity of the problems, developing exact and approximation algorithms, exploring effective mathematical formulations, solution search strategies and heuristics. In particular, mathematical models such as linear and nonlinear mixed integer programming, disjunctive programming and stochastic programming that arise in telecommunication, data mining, logistics and production planning are investigated.
People: Ceyda Oğuz, Sibel Salman, Serpil Sayın, Metin Türkay, Deniz Aksen
Production Systems and Scheduling
The research in production systems focuses on a number of design and optimization issues in production planning, control, and scheduling. Our research interests cover large-scale optimization formulations of production planning problems, design of production and inventory control policies in multi-item and/or multi-stage systems, and scheduling of tasks at the detailed shop-floor control level. Some recent topics of interest within this framework include: development of real-time production planning systems, integration of advance demand information and pricing in production control mechanisms, production control with subcontracting, just-in-time production systems, earliness-tardiness scheduling problems, scheduling of multi-stage hybrid flow shops, and cyclic scheduling problems.
People: Yaman Arkun, Selçuk Karabatı, Fikri Karaesmen, Onur Kaya, Ceyda Oğuz, Barış Tan, Metin Türkay
Service Operations
Industrial engineering techniques are widely applicable in many different areas. Now that service industry is growing rapidly (about 60% of Turkish GDP and about 80% of US GDP are earned from service industry), efficiency in service systems has become extremely important. Our research interests on the area primarily cover applications on call centers, hospitals, telecommunication systems. We generally develop stochastic models for these systems, which evaluates certain performance measures of these systems, or identifies optimal dynamic or static control policies according to certain objectives.
People: Zeynep Akşin, Evrim Güneş, Fikri Karaesmen, Lerzan Örmeci
Supply Chain Management
A supply chain is the collection of physical, financial, and information networks that involve the advancement of materials, funds, and information through the entire logistics process, from the procurement of raw materials to delivery of finished products or services to the consumer. The supply chain includes all vendors, service providers, customers, and intermediaries. We develop strategic and operational policies which go into improving the way a supply chain operates, using optimization, simulation, and other operations research tools.
People: Yalçın Akçay, Evrim Güneş, Fikri Karaesmen, Onur Kaya, Lerzan Örmeci Barış Tan, Metin Türkay